Mazzie was born in Rockford, Illinois and graduated from Western Michigan University, where she studied theater and music. With an early interest in the theatre, Mazzie began to perform and sing in church choir at the age of 8 and to study voice at the age of 12. She continued to act in school and at college and in summer stock, where she was an apprentice at the Barn Theatre in Augusta, Michigan. She is married to Broadway actor Jason Danieley.

Read more about Marin Mazzie on Last.fm.